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dc.contributorid-ID
dc.creatorSusilarini, Ni Ketut; Center for Biomedical and Basic Technology of Health, National Institute of Health Research and Development, Ministry of Health
dc.creatorSetiawaty, Vivi; Center for Biomedical and Basic Technology of Health, National Institute of Health Research and Development, Ministry of Health
dc.date2013-07-04
dc.date.accessioned2019-12-17T00:36:24Z
dc.date.available2019-12-17T00:36:24Z
dc.identifierhttp://ejournal.litbang.depkes.go.id/index.php/HSJI/article/view/3095
dc.identifier10.22435/hsji.v4i1 Jun.3095.37-40
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/handle/123456789/80985
dc.descriptionAbstrakLatar belakang: Infeksi virus Influenza A dapat menyebabkan wabah di seluruh dunia. Wabah virus H1N1 terjadi di Indonesia pada bulan April 2009. Sebanyak 1892 kasus terduga H1N1 dilaporkan antara April dan akhir Desember 2009. Dari 1892 kasus yang terduga, hanya 809 dikonfirmasi terinfeksi virus H1N1. Karena virus strain baru, maka perlu diketahui persentase kasus yang mengembangkan antibodi anti H1N1 setelah infeksi pertama kali. Metode: Penelitian menggunakan sera yang disimpan dari yang dikumpulkan pada tahun 2009 yang disimpan pada-70 oC di laboratorium virologi di Lembaga Penelitian dan Pengembangan Kesehatan. Ujia yang digunakan ialah uji HI untuk menentukan kekebalan setelah infeksi Influenza A/H1N1pdm09. Hasil: Hanya sebagian kecil kasus terinfeksi flu A/H1N1pdm09 selama wabah mengembangkan antibodi pelindung anti H1N1pdm09. Dari 205 sera yang diperiksa, 38 kasus (18,5%) mengembangkan antibodi anti H1N1pdm09 dengan HI titer ≥1:40. Kesimpulan: Sebanyak 18,5% kasus yang mengembangkan antibodi anti H1N1pdm09 di antara kasus terinfeksi flu A/H1N1pdm09 selama wabah 2009. (Health Science Indones 2013;1:37-40) Keywords: Influenza, antibody, pandemic, 2009 AbstractBackground: Influenza A virus infection can cause pandemic influenza worldwide. The outbreak of the H1N1 virus occurred in Indonesia in April 2009. A total of 1892 suspected cases of H1N1 were reported between April and the end of December 2009. From 1892 suspected cases, there were only 809 confirmed infected by the H1N1 virus. Since the virus is a new strain, we wanted to know how many cases developed antibody anti H1N1 after the first infection occurred. Methods: We used archived sera which was collected in 2009 and stored at -70oC in the virology laboratory of the National Institute of Health Research and Development. We used the HI assay to determine the immunity after infection of Influenza A/H1N1pdm09 in 2009. Results: Only a small proportion of cases infected during an outbreak of flu A/H1N1pdm09 develop protective antibodies anti H1N1pdm09. Of 205 sera were examined, 38 cases (18.5%) developed anti H1N1pdm09 with HI antibody titer ≥1:40. Conclusion: A total of 18.5% of cases develop antibodies anti H1N1pdm09 among A/H1N1pdm09 flu cases during the 2009 outbreak. (Health Science Indones 2013;1:37-40)Keywords:Influenza, antibody, pandemic, 2009id-ID
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dc.publisherBadan Penelitian dan Pengembangan Kesehatanen-US
dc.rightsThe Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Health Science Journal of Indonesia and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development) as publisher of the journal.Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc. , will be allowed only with a written permission from Health Science Journal of Indonesia and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development).Health Science Journal of Indonesia and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development), the Editors and the Advisory International Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal.
dc.rightsUnder the terms of Indonesian Goverment Copyright Law, Health Science Journal of Indonesia must formally obtain transfer of copyright before an article can be published. Health Science Journal of Indonesia grants to the author (and to all coauthors) the right to present orally in any forum all or part of the work. It is also stipulated that all graphics including figures, tables and charts may be republished with permission from Health Science Journal of Indonesia. In consideration of the fact that Health Science Journal of Indonesia undertakes to publish my article: I affirm that the material has not been previously published and that I (and my coauthors) own and have not transferred elsewhere any rights to the article.I affirm that I (and my coauthors) have obtained written permission to use any previously copyrighted material included in the article and that such documentation will be forwarded to Health Science Journal of Indonesia simultaneously with the article. I further affirm that I (and my coauthors) have stated any possible conflicts of interest within the article.I (and my coauthors) hereby assign and transfer to Health Science Journal of Indonesia all rights of copyright ownership and permission to the article, including without limitation or restriction, all rights of reproduction, derivation, distribution, sale, reuse, and display of the of the work, in whole or in part, including recompilation and stand-alone publication, in any and all forms of media now or hereafter known, including all electronic and digital media, as protected by the laws of the Republic of Indonesia and foreign countries and to authorize others to make such uses of the work. These rights will become the property of Health Science Journal of Indonesia from the date of acceptance of the article for publication and extend for the life of the copyright. I understand that Health Science Journal of Indonesia, as copyright owner, has authority to grant permission to reproduce the article.
dc.sourceHealth Science Journal of Indonesia; Vol 4, No 1 Jun (2013); 37-40en-US
dc.sourceHealth Science Journal of Indonesia; Vol 4, No 1 Jun (2013); 37-40id-ID
dc.subjecthealthid-ID
dc.subjectInfluenza, antibody, pandemic, 2009id-ID
dc.subjectHealthid-ID
dc.titleAntibody anti H1N1pdm09 detection from Influenza A outbreak cases in Indonesia 2009id-ID
dc.typePeer-reviewed Articleen-US


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